Adrenaline infusion until adequate systolic blood pressure more than 100mg hg is restored; adrenaline reduces the effects of chloroquine on the heart through its inotropic and vasoconstrictor effects.

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It has been found that certain strains of Pfalciparum have become resistant to 4-aminoquinoline compoundsincluding chloroquine and hydroxychloroquineChloroquine resistance is widespread andat presentis particularly prominent in various parts of the world including sub-Saharan AfricaSoutheast Asiathe Indian subcontinentand over large portions of South Americaincluding the Amazon basin 1

If your symptoms or health problems do not get better or if they become worsecall your doctorDo not share your drugs with others and do not take anyone else’s drugsKeep a list of all your drugsprescriptionnatural productsvitaminsOTCwith youGive this list to your doctorTalk with the doctor before starting any new drugincluding prescription or OTCnatural productsor vitaminsSome drugs may have another patient information leafletCheck with your pharmacistIf you have any questions about chloroquineplease talk with your doctornursepharmacistor other health care providerIf you think there has been an overdosecall your poison control center or get medical care right awayBe ready to tell or show what was takenhow muchand when it happened.

All patients on long-term therapy with this preparation should be questioned and examined periodicallyincluding testing knee and ankle reflexesto detect any evidence of muscular weaknessIf weakness occursdiscontinue the drug.

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