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Do not use potassium supplements or salt substitutes while you are taking hydrochlorothiazide and losartanunless your doctor has told you to.

Use an effective form of birth control if you’re a woman of childbearing age.

In rare caseshydrochlorothiazide and losartan can cause a condition that results in the breakdown of skeletal muscle tissueleading to kidney failureCall your doctor right away if you have unexplained muscle paintendernessor weakness especially if you also have feverunusual tirednessand dark colored urine.

Hypertensionnot for initial therapy unless HTN is severeTo reduce stroke in hypertensive patients with left ventricular hypertrophyLVHthis benefit may not apply to black patients.

It is a single product containing 2 medicationslosartan and hydrochlorothiazideLosartan is in a class of medications called angiotensin II receptor antagonistsIt works by blocking the action of certain natural substances that tighten blood vesselsallowing the blood to flow more smoothly and the heart to pump more efficientlyHydrochlorothiazide is in a class of medications called diureticsorwater pillsIt works by causing the kidneys to get rid of unneeded water and salt from the body into the urine.

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